Entry Detail


General Information

Database ID: LDA0021017
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:EMX2OS
Full Name:EMX2 opposite strand/antisense RNA
Category:LncRNA
Species:Homo sapiens
Synonyms:EMX2-AS1|NCRNA00045
Chromosome:10
Strand:-
Coordinate:
Start Site(bp):117484293End Site(bp):117545068
External Links:
Ensembl ID:ENSG00000229847
Ensembl Transcript ID:N/A
Entrez Gene:196047.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:10   
More Information
Causal Disease Number:6
Network:
Top Causal Diseases:
Ovarian Neoplasms  (Score: 0.731059)
Prostatic Neoplasms  (Score: 0.731059)
Ovarian Neoplasms  (Score: 0.731059)
Prostatic Neoplasms  (Score: 0.731059)
Wilms Tumor  (Score: 0.548294)
Wilms Tumor  (Score: 0.548294)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D015673
Disease Name:Fatigue Syndrome, Chronic
Category:MeSH
Type:Musculoskeletal Diseases
Define:A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
Alias:Fatigue Syndrome, Chronic//Chronic Fatigue Syndromes//Fatigue Syndromes, Chronic//Infectious Mononucleosis-Like Syndrome, Chronic//Infectious Mononucleosis Like Syndrome, Chronic//Royal Free Disease//Chronic Fatigue and Immune Dysfunction Syndrome//Postviral Fatigue Syndrome//Fatigue Syndrome, Postviral//Fatigue Syndromes, Postviral//Postviral Fatigue Syndromes//Syndrome, Postviral Fatigue//Syndromes, Postviral Fatigue//Systemic Exertion Intolerance Disease//Myalgic Encephalomyelitis//Encephalomyelitis, Myalgic//Chronic Fatigue Syndrome//Chronic Fatigue-Fibromyalgia Syndrome//Chronic Fatigue Fibromyalgia Syndrome//Chronic Fatigue-Fibromyalgia Syndromes//Fatigue-Fibromyalgia Syndrome, Chronic//Fatigue-Fibromyalgia Syndromes, Chronic//Chronic Fatigue Disorder//Chronic Fatigue Disorders//Fatigue Disorder, Chronic//Fatigue Disorders, Chronic

 

Disease Association Statistics

Total Associated ncRNA Number:6   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:30119681
Disease Name:Fatigue Syndrome, Chronic
Sample:peripheral blood mononuclear cells
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description: LncRNAs NTT, MIAT and EmX2OS levels were found to be significantly elevated in ME/CFS patients as compared with healthy controls.
Causality:No
Causal Description:
Clinical-realted Application: