Entry Detail

General Information

Database ID: LDA0021416
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:CRNDE
Full Name:colorectal neoplasia differentially expressed
Category:LncRNA
Species:Homo sapiens
Synonyms:CRNDEP|LINC00180|NCRNA00180|PNAS-108|lincIRX5
Chromosome:16
Strand:-
Coordinate:
Start Site(bp):54918863End Site(bp):54928886
External Links:
Ensembl ID:ENSG00000245694
Ensembl Transcript ID:N/A
Entrez Gene:643911.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:58   
More Information
Causal Disease Number:54
Network:
Top Causal Diseases:
Carcinoma, Hepatocellular  (Score: 1)
Uterine Cervical Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Uterine Cervical Neoplasms  (Score: 1)
Sepsis  (Score: 0.999893)
Sepsis  (Score: 0.999893)
Carcinoma, Non-Small-Cell Lung  (Score: 0.999358)
Carcinoma, Non-Small-Cell Lung  (Score: 0.999358)
Nasopharyngeal carcinoma  (Score: 0.985791)
Colorectal Neoplasms  (Score: 0.985791)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:687D018197
Disease Name:hepatoblastomaHepatoblastoma
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)
Alias:Hepatoblastoma//Hepatoblastomas

 

Disease Association Statistics

Total Associated ncRNA Number:36   
More Information
Causal ncRNA Number:30
Network:
Top Causal ncRNAs:
ZFAS1  (Score: 0.731059)
LINC00205  (Score: 0.731059)
GAS5  (Score: 0.731059)
LUCAT1  (Score: 0.731059)
LINC01023  (Score: 0.731059)
circHMGCS1  (Score: 0.731059)
circSETD3  (Score: 0.731059)
hsa_circ_0000594  (Score: 0.731059)
OIP5-AS1  (Score: 0.731059)
MIR210HG  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:Western Blot//Wound Healing Assay//qRT-PCR//MTT//Luciferase Report Assay
Weak Evidence:

 

Reference

[1] PubMed ID:32182608
Disease Name:Hepatoblastoma
Sample:HB tissues
Dysfunction Pattern:regulation[MiR-203/VEGFA Axis]
Validated Method:Western Blot//Wound Healing Assay//qRT-PCR//MTT//Luciferase Report Assay
Description: Our data revealed that miR-203 expression was decreased in HB tissues, while long non-coding RNA (lncRNA) CRNDE expression was increased. lncRNA CRNDE targets the miR-203/VEGFA axis and promotes angiogenesis in HB.
Causality:No
Causal Description:
Clinical-realted Application:The dysregulation of miR-203 and CRNDE was closely related to tumour size and stage.