Entry Detail

General Information

Database ID: LDA0021472
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:H19
Full Name:H19, imprinted maternally expressed transcript
Category:LncRNA
Species:Mus musculus
Synonyms:EyeLinc6
Chromosome:7
Strand:-
Coordinate:
Start Site(bp):142129267End Site(bp):142131883
External Links:
Ensembl ID:ENSMUSG00000000031
Ensembl Transcript ID:N/A
Entrez Gene:14955.0
NONCODE ID:N/A
RefSeq Accession:NR_130973.1

 

ncRNA Association Statistics

Total Associated Disease Number:214   
More Information
Causal Disease Number:122
Network:
Top Causal Diseases:
Stomach Neoplasms  (Score: 1)
Glioma  (Score: 1)
Glioma  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D006338
Disease Name:Heart Neoplasms
Category:MeSH
Type:Neoplasms
Define:Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.
Alias:Heart Neoplasms//Heart Neoplasm//Neoplasm, Heart//Neoplasms, Heart//Cardiac Tumors//Neoplasms, Cardiac//Cardiac Neoplasms//Cardiac Neoplasm//Neoplasm, Cardiac//Cardiac Tumor//Tumor, Cardiac//Tumors, Cardiac//Primary Cardiac Tumors, Childhood//Myocardial Tumors (Rhabdomyomas and Fibromas)//Myocardial Tumor (Rhabdomyomas and Fibromas)//Tumor, Myocardial (Rhabdomyomas and Fibromas)//Tumors, Myocardial (Rhabdomyomas and Fibromas)//Cardiac Carcinoma//Carcinoma, Cardiac//Carcinomas, Cardiac//Cardiac Carcinomas//Heart Cancer//Cancer, Heart//Cancers, Heart//Heart Cancers//Cardiac Cancer//Cancer, Cardiac//Cancers, Cardiac//Cardiac Cancers//Heart Tumor//Heart Tumors//Tumor, Heart//Tumors, Heart//Intracavitary Tumors of the Heart

 

Disease Association Statistics

Total Associated ncRNA Number:2   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:Western Blot//qRT-PCR//Luciferase Report Assay//Cell Apoptosis Assay//Colony Formation Assay
Weak Evidence:

 

Reference

[1] PubMed ID:30843379
Disease Name:Heart Neoplasms
Sample:cardiac cancer tissues
Dysfunction Pattern:Expression[highly expressed]
Validated Method:Western Blot//qRT-PCR//Luciferase Report Assay//Cell Apoptosis Assay//Colony Formation Assay
Description:The study results indicated that H19, miR-130a-3p, and miR-17-5p expressions within cardiac cancer tissues were significantly beyond those within adjacent nontumor tissues (P < 0.05), and H19 expression was positively correlated with both miR-130a-3p (rs = 0.43) and miR-17-5p (rs = 0.49) expressions.
Causality:No
Causal Description:
Clinical-realted Application: