Entry Detail

General Information

Database ID: LDA0021508
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:GRB10
Full Name:growth factor receptor bound protein 10
Category:LncRNA
Species:Homo sapiens
Synonyms:GRB-IR|Grb-10|IRBP|MEG1|RSS
Chromosome:7
Strand:-
Coordinate:
Start Site(bp):50590068End Site(bp):50793453
External Links:
Ensembl ID:ENSG00000106070
Ensembl Transcript ID:N/A
Entrez Gene:2887.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:2   
More Information
Causal Disease Number:0
Network:
Top Causal Diseases:
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:90
Disease Name:degenerative disc disease
Category:Disease Ontology
Type:Nervous System Diseases
Define:A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc.
Alias:cervical disc degenerative disease//intervertebral disc degeneration//lumbar disc degeneration//vertebral disc disease

 

Disease Association Statistics

Total Associated ncRNA Number:4   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qPCR//PCR
Weak Evidence:

 

Reference

[1] PubMed ID:36251122
Disease Name:degenerative disc disease
Sample:60 cases of LDDD
Dysfunction Pattern:Expression(lower expressed)
Validated Method:qPCR//PCR
Description:Compared to HCs, decreased accumulation of GRB10 RNA was only observed in LDDD group, but not in SJP, LDH, PS and EN groups. With plasma expression level of GRB10 measured before treatment as a biomarker, LDDD patients were separated from SJP, LDH, PS, EN and HC groups.
Causality:No
Causal Description:
Clinical-realted Application: