Entry Detail

General Information

Database ID: LDA0021543
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:H19
Full Name:H19, imprinted maternally expressed transcript
Category:LncRNA
Species:Mus musculus
Synonyms:EyeLinc6
Chromosome:7
Strand:-
Coordinate:
Start Site(bp):142129267End Site(bp):142131883
External Links:
Ensembl ID:ENSMUSG00000000031
Ensembl Transcript ID:N/A
Entrez Gene:14955.0
NONCODE ID:N/A
RefSeq Accession:NR_130973.1

 

ncRNA Association Statistics

Total Associated Disease Number:214   
More Information
Causal Disease Number:122
Network:
Top Causal Diseases:
Stomach Neoplasms  (Score: 1)
Glioma  (Score: 1)
Glioma  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:0050850
Disease Name:diabetic encephalopathy
Category:Disease Ontology
Type:Endocrine System Diseases
Define:A brain disease that is characterized by functional impairment of cognition, cerebral signal conduction, neurotransmission and synaptic plasticity, and underlying structural pathology associated with diabetes.
Alias:

 

Disease Association Statistics

Total Associated ncRNA Number:2   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:Western Blot//Transfection//qRT-PCR//Luciferase Report Assay//ELISA//IF
Weak Evidence:

 

Reference

[1] PubMed ID:35961529
Disease Name:diabetic encephalopathy
Sample:DE rats, HT-22 cells
Dysfunction Pattern:Interaction(H19/miR-15b/BACE1 axis)
Validated Method:Western Blot//Transfection//qRT-PCR//Luciferase Report Assay//ELISA//IF
Description:MiR-15b was downregulated while H19 and BACE1 were upregulated in the hippocampus CA3 regionof DE rats and AGEs-treated HT-22 cells.
Causality:No
Causal Description:
Clinical-realted Application: