Entry Detail

General Information

Database ID: LDA0021544
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:H19
Full Name:H19, imprinted maternally expressed transcript
Category:LncRNA
Species:Mus musculus
Synonyms:EyeLinc6
Chromosome:7
Strand:-
Coordinate:
Start Site(bp):142129267End Site(bp):142131883
External Links:
Ensembl ID:ENSMUSG00000000031
Ensembl Transcript ID:N/A
Entrez Gene:14955.0
NONCODE ID:N/A
RefSeq Accession:NR_130973.1

 

ncRNA Association Statistics

Total Associated Disease Number:214   
More Information
Causal Disease Number:122
Network:
Top Causal Diseases:
Stomach Neoplasms  (Score: 1)
Glioma  (Score: 1)
Glioma  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Stomach Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Colorectal Neoplasms  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D049912
Disease Name:Growth Hormone-Secreting Pituitary Adenoma
Category:MeSH
Type:Neoplasms
Define:A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH HORMONE leads to ACROMEGALY.
Alias:Growth Hormone-Secreting Pituitary Adenoma//GH-Secreting Pituitary Adenoma//GH Secreting Pituitary Adenoma//GH-Secreting Pituitary Adenomas//Pituitary Adenomas, GH-Secreting//Pituitary Adenoma, GH-Secreting//Pituitary Adenoma, GH Secreting//Pituitary Growth Hormone-Secreting Adenoma//Pituitary Growth Hormone Secreting Adenoma//Somatotroph Adenoma//Adenoma, Somatotroph//Adenomas, Somatotroph//Somatotroph Adenomas//Acromegaly Due To Pituitary Adenoma//Pituitary Adenoma, Growth Hormone-Secreting//Pituitary Adenoma, Growth Hormone Secreting//Somatotrophinoma, Familial//Isolated Familial Somatotropinoma//Somatotropinoma, Familial Isolated

 

Disease Association Statistics

Total Associated ncRNA Number:4   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:29604339
Disease Name:Growth Hormone-Secreting Pituitary Adenoma
Sample:
Dysfunction Pattern:Expression [highly expressed]
Validated Method:qRT-PCR
Description:Our results revealed that the expression of lncRNA H19 was remarkably higher in invasive GHPAs, however, there was no significant differences between the expression of lncRNA MALAT-1 in invasive GHPAs and non-invasive GHPAs, suggesting that lncRNA H19 may play an important role in GHPA invasion. LncRNA H19 might be a target for the study of GHPAs invasion, and a potential index for the diagnosis or prognosis of GHPAs.
Causality:No
Causal Description:
Clinical-realted Application: