Entry Detail

General Information

Database ID: LDA0021575
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:HNF1A-AS1
Full Name:HNF1A antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:C12orf27|HAS1|HASTER|NCRNA00262
Chromosome:12
Strand:-
Coordinate:
Start Site(bp):120969838End Site(bp):120972292
External Links:
Ensembl ID:ENSG00000241388
Ensembl Transcript ID:N/A
Entrez Gene:283460.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:26   
More Information
Causal Disease Number:20
Network:
Top Causal Diseases:
Colorectal Neoplasms  (Score: 0.985791)
Colorectal Neoplasms  (Score: 0.985791)
neuroendocrine carcinoma  (Score: 0.731059)
Breast Neoplasms  (Score: 0.731059)
Carcinoma, Non-Small-Cell Lung  (Score: 0.731059)
Glioblastoma  (Score: 0.731059)
Glioma  (Score: 0.731059)
Esophageal Neoplasms  (Score: 0.731059)
Osteosarcoma  (Score: 0.731059)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:4006
Disease Name:bladder urothelial carcinoma
Category:Disease Ontology
Type:Neoplasms
Define:A bladder carcinoma that has_material_basis_in transitional cells located_in the lining of the bladder.
Alias:bladder transitional cell carcinoma//transitional cell carcinoma of bladder//urinary bladder urothelial carcinoma//urothelial bladder carcinoma

 

Disease Association Statistics

Total Associated ncRNA Number:10   
More Information
Causal ncRNA Number:2
Network:
Top Causal ncRNAs:
MILIP  (Score: 0.731059)
MILIP  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:29762827
Disease Name:bladder urothelial carcinoma
Sample:UCB tissues
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description:Data showed that the majority of UCB tissues showed higher HNF1A-AS1 levels than the corresponding normal tissues controls (p < 0.01).
Causality:No
Causal Description:
Clinical-realted Application:Statistical assay revealed that high HNF1A-AS1 expression was significantly correlated with histological grade (p = 0.008), tumor stage T (p = 0.003) and lymph nodes metastasis (p = 0.007). In addition, the overall survival time of patients with high HNF1A-AS1 expression was significantly shorter compared to those with low HNF1A-AS1 expression.