Entry Detail

General Information

Database ID: LDA0021592
Species: Homo sapiens
Confidence Score: 0.548294
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:HEIH
Full Name:hepatocellular carcinoma up-regulated EZH2-associated long non-coding RNA
Category:LncRNA
Species:Homo sapiens
Synonyms:HCCAT2|LINC-HEIH|LINC00848|lncRNA-HEIH
Chromosome:5
Strand:-
Coordinate:
Start Site(bp):180829954End Site(bp):180831618
External Links:
Ensembl ID:ENSG00000278970
Ensembl Transcript ID:N/A
Entrez Gene:100859930.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:22   
More Information
Causal Disease Number:20
Network:
Top Causal Diseases:
Stomach Neoplasms  (Score: 0.999893)
Stomach Neoplasms  (Score: 0.999893)
Breast Neoplasms  (Score: 0.985791)
Triple Negative Breast Neoplasms  (Score: 0.985791)
Ovarian Neoplasms  (Score: 0.985791)
Esophageal Squamous Cell Carcinoma  (Score: 0.985791)
Carcinoma, Non-Small-Cell Lung  (Score: 0.985791)
Breast Neoplasms  (Score: 0.985791)
Triple Negative Breast Neoplasms  (Score: 0.985791)
Ovarian Neoplasms  (Score: 0.985791)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:3393D003324
Disease Name:coronary artery diseaseCoronary Artery Disease
Category:Disease OntologyMeSH
Type:Cardiovascular Diseases
Define:An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Alias:CHD//Coronary disease//coronary arteriosclerosis//coronary heart diseaseCoronary Artery Disease//Artery Disease, Coronary//Artery Diseases, Coronary//Coronary Artery Diseases//Left Main Coronary Artery Disease//Left Main Disease//Left Main Diseases//Left Main Coronary Disease//Coronary Arteriosclerosis//Arterioscleroses, Coronary//Coronary Arterioscleroses//Atherosclerosis, Coronary//Atheroscleroses, Coronary//Coronary Atheroscleroses//Coronary Atherosclerosis//Arteriosclerosis, Coronary

 

Disease Association Statistics

Total Associated ncRNA Number:134   
More Information
Causal ncRNA Number:24
Network:
Top Causal ncRNAs:
MALAT1  (Score: 1)
MALAT1  (Score: 1)
LINC00968  (Score: 0.985791)
LINC00968  (Score: 0.985791)
uc003pxg.1  (Score: 0.731059)
GAS5  (Score: 0.731059)
AGAP2-AS1  (Score: 0.731059)
circLDLR  (Score: 0.731059)
circNPHP4  (Score: 0.731059)
NEAT1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:
Weak Evidence:Bioinformatics Analysis

 

Reference

[1] PubMed ID:35003390
Disease Name:Coronary Artery Disease
Sample:plasma of patients with CAD
Dysfunction Pattern:Expression(highly expressed)
Validated Method:Bioinformatics Analysis
Description:The expression of lncRNA-HEIH in plasma of patients with CAD was remarkably higher than that in the control subjects and was verified to be relevant to the severity of CAD.
Causality:No
Causal Description:
Clinical-realted Application:The expression of lncRNA-HEIH in plasma of patients with CAD was remarkably higher than that in the control subjects and was verified to be relevant to the severity of CAD. Meanwhile, it was found that CAD patients with high expression of lncRNA-HEIH had higher rates of dyslipidemia as well as CAD family history and higher overall incidence of major cardiac adverse events than those with low expression of lncRNA-HEIH.