Entry Detail

General Information

Database ID: LDA0021599
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:HCG22
Full Name:HLA complex group 22 (gene/pseudogene)
Category:LncRNA
Species:Homo sapiens
Synonyms:PBMUCL2
Chromosome:6
Strand:+
Coordinate:
Start Site(bp):31053449End Site(bp):31059849
External Links:
Ensembl ID:ENSG00000228147
Ensembl Transcript ID:N/A
Entrez Gene:285834.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:4   
More Information
Causal Disease Number:2
Network:
Top Causal Diseases:
Squamous Cell Carcinoma of Head and Neck  (Score: 0.999893)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.999893)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:13378D009080
Disease Name:Kawasaki diseaseMucocutaneous Lymph Node Syndrome
Category:Disease OntologyMeSH
Type:Cardiovascular Diseases
Define:A lymphadenitis characterized by swelling of cervical lymph nodes in infants and young children and inflammation of medium-sized blood vessels located_in body, has_symptom fever, has_symptom congestion of ocular conjunctivae, has_symptom reddening of lips, has_symptom reddening of oral cavity, has_symptom protuberance of tongue papillae and has_symptom edema of extremities.An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities.
Alias:Kawasaki's disease//MLNS//acute febrile MCLS//acute febrile mucocutaneous lymph node syndrome//mucocutaneous lymph node syndromeMucocutaneous Lymph Node Syndrome//Kawasaki Syndrome//Lymph Node Syndrome, Mucocutaneous//Kawasaki Disease

 

Disease Association Statistics

Total Associated ncRNA Number:18   
More Information
Causal ncRNA Number:6
Network:
Top Causal ncRNAs:
SLCO4A1  (Score: 0.731059)
SOCS2-AS1  (Score: 0.731059)
hsa_circ_3302  (Score: 0.731059)
SLCO4A1  (Score: 0.731059)
SOCS2-AS1  (Score: 0.731059)
hsa_circ_3302  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:34373708
Disease Name:Mucocutaneous Lymph Node Syndrome
Sample:serum
Dysfunction Pattern:Regulation
Validated Method:qRT-PCR
Description:The results indicated that the serum levels of lncRNAs SRA and HCG22 were higher in patients with acute KD compared with those in healthy controls.
Causality:No
Causal Description:
Clinical-realted Application:B-type natriuretic peptide (BNP) and C-reactive protein were positively correlated with HCG22 in patients with acute KD, while total cholesterol and low-density lipoprotein were negatively correlated with HCG22 in patients with acute KD.