Entry Detail

General Information

Database ID: LDA0021601
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:HCG14
Full Name:HLA complex group 14
Category:LncRNA
Species:Homo sapiens
Synonyms:dJ111M5.4
Chromosome:6
Strand:+
Coordinate:
Start Site(bp):28896530End Site(bp):28897320
External Links:
Ensembl ID:ENSG00000237010
Ensembl Transcript ID:N/A
Entrez Gene:414760.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:2   
More Information
Causal Disease Number:0
Network:
Top Causal Diseases:
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D002446
Disease Name:Celiac Disease
Category:MeSH
Type:Digestive System Diseases
Define:A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION.
Alias:Celiac Disease//Disease, Celiac//Gluten Enteropathy//Enteropathies, Gluten//Enteropathy, Gluten//Gluten Enteropathies//Gluten-Sensitive Enteropathy//Enteropathies, Gluten-Sensitive//Enteropathy, Gluten-Sensitive//Gluten Sensitive Enteropathy//Gluten-Sensitive Enteropathies//Sprue, Celiac//Sprue, Nontropical//Nontropical Sprue//Celiac Sprue//Sprue

 

Disease Association Statistics

Total Associated ncRNA Number:2   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//Genotyping
Weak Evidence:

 

Reference

[1] PubMed ID:29601440
Disease Name:Celiac Disease
Sample:HLA-DR-DQ loci
Dysfunction Pattern:Regulation(NOD1)
Validated Method:qRT-PCR//Genotyping
Description: Expression of HCG14 was slightly downregulated in epithelial cells isolated from duodenal biopsies of celiac patients, and eQTL analysis revealed that polymorphisms in HCG14 region were associated with decreased NOD1 expression in duodenal intestinal cells.
Causality:No
Causal Description:
Clinical-realted Application: