Entry Detail

General Information

Database ID: LDA0021655
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:FER1L4
Full Name:fer-1 like family member 4 (pseudogene)
Category:LncRNA
Species:Homo sapiens
Synonyms:C20orf124
Chromosome:20
Strand:-
Coordinate:
Start Site(bp):35558737End Site(bp):35607562
External Links:
Ensembl ID:ENSG00000088340
Ensembl Transcript ID:N/A
Entrez Gene:80307.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:32   
More Information
Causal Disease Number:22
Network:
Top Causal Diseases:
Osteosarcoma  (Score: 0.999893)
Osteosarcoma  (Score: 0.999893)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.985791)
Lung Neoplasms  (Score: 0.985791)
Carcinoma, Hepatocellular  (Score: 0.985791)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.985791)
Lung Neoplasms  (Score: 0.985791)
Carcinoma, Hepatocellular  (Score: 0.985791)
Colorectal Neoplasms  (Score: 0.959542)
Colorectal Neoplasms  (Score: 0.959542)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:7148D001172
Disease Name:rheumatoid arthritisArthritis, Rheumatoid
Category:Disease OntologyMeSH
Type:Musculoskeletal Diseases
Define:An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
Alias:Arthritis or polyarthritis, rheumatic//atrophic ArthritisArthritis, Rheumatoid//Rheumatoid Arthritis

 

Disease Association Statistics

Total Associated ncRNA Number:134   
More Information
Causal ncRNA Number:64
Network:
Top Causal ncRNAs:
GAS5  (Score: 1)
GAS5  (Score: 1)
NEAT1  (Score: 1)
NEAT1  (Score: 1)
LINC00638  (Score: 0.999893)
THRIL  (Score: 0.999893)
THRIL  (Score: 0.999893)
LINC00638  (Score: 0.999893)
ZFAS1  (Score: 0.985791)
MEG3  (Score: 0.985791)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR//FISH//MTT//Western Blot
Weak Evidence:

 

Reference

[1] PubMed ID:31694750
Disease Name:Arthritis, Rheumatoid
Sample:synovial tissues
Dysfunction Pattern:Interaction[targeting NLRC5 ]
Validated Method:qRT-PCR//MTT//Western Blot//FISH
Description:The level of FER1L4 significantly reduced in STs and FLSs, whereas the nucleotide oligomerisation domain-like receptors 5 (NLRC5) levels were increased.These results indicated that FER1L4 regulates RA via targeting NLRC5 potentially.
Causality:No
Causal Description:
Clinical-realted Application: