Entry Detail


General Information

Database ID: LDA0021734
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:FAS-AS1
Full Name:FAS antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:FAS-AS|FASAS|SAF
Chromosome:10
Strand:-
Coordinate:
Start Site(bp):88991422End Site(bp):88992975
External Links:
Ensembl ID:N/A
Ensembl Transcript ID:N/A
Entrez Gene:100302740.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:8   
More Information
Causal Disease Number:2
Network:
Top Causal Diseases:
Carcinoma, Non-Small-Cell Lung  (Score: 0.985791)
Carcinoma, Non-Small-Cell Lung  (Score: 0.985791)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D008179
Disease Name:Lupus Erythematosus, Discoid
Category:MeSH
Type:Skin and Connective Tissue Diseases
Define:A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.
Alias:Lupus Erythematosus, Discoid//Discoid Lupus Erythematosus//Lupus Erythematosus, Chronic Cutaneous//Lupus Erythematosus, Cutaneous, Chronic

 

Disease Association Statistics

Total Associated ncRNA Number:14   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:32614682
Disease Name:Lupus Erythematosus, Discoid
Sample:serum
Dysfunction Pattern:Expression[lower expressed]
Validated Method:qRT-PCR
Description:There was a significant relative increased serum FAS-AS1 (median (IQR) 2.19 (0.13-8.62) and a significant reduced PVT1 (median (IQR) 0.52 (0.01-7.55) in SLE patients compared to controls (P < 0.0001 for FAS-AS1 and = 0.007 for PVT1).
Causality:No
Causal Description:
Clinical-realted Application: