Entry Detail

General Information

Database ID: LDA0021800
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:GABPB1-AS1
Full Name:GABPB1 antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:-
Chromosome:15
Strand:+
Coordinate:
Start Site(bp):50354174End Site(bp):50358312
External Links:
Ensembl ID:ENSG00000244879
Ensembl Transcript ID:N/A
Entrez Gene:100129387.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:6   
More Information
Causal Disease Number:4
Network:
Top Causal Diseases:
Uterine Cervical Neoplasms  (Score: 0.731059)
Glioma  (Score: 0.731059)
Uterine Cervical Neoplasms  (Score: 0.731059)
Glioma  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:12894D012859
Disease Name:Sjogren's syndromeSjogren's Syndrome
Category:Disease OntologyMeSH
Type:Musculoskeletal Diseases
Define:An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
Alias:Sicca syndrome//Sjogren syndrome//xerodermosteosisSjogren's Syndrome//Sjogrens Syndrome//Syndrome, Sjogren's//Sjogren Syndrome//Sicca Syndrome//Syndrome, Sicca

 

Disease Association Statistics

Total Associated ncRNA Number:62   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:34284720
Disease Name:Sjogren's Syndrome
Sample:PBMCs of 30 patients with pSS and 15 healthy persons
Dysfunction Pattern:Expression(highly expressed)
Validated Method:qRT-PCR//Bioinformatics Analysis
Description:Real-time PCR revealed that GABPB1-AS1 and PSMA3-AS1 were significantly up-regulated 3.0- and 1.4-fold in the pSS group, respectively. The GABPB1-AS1 expression level was positively correlated with the percentage of B cells and IgG levels.
Causality:No
Causal Description:
Clinical-realted Application: