Entry Detail


General Information

Database ID: LDA0021815
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:FTX
Full Name:FTX transcript, XIST regulator
Category:LncRNA
Species:Homo sapiens
Synonyms:LINC00182|MIR374AHG|NCRNA00182
Chromosome:X
Strand:-
Coordinate:
Start Site(bp):74028136End Site(bp):74293574
External Links:
Ensembl ID:ENSG00000230590
Ensembl Transcript ID:N/A
Entrez Gene:100302692.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:24   
More Information
Causal Disease Number:16
Network:
Top Causal Diseases:
Colorectal Neoplasms  (Score: 0.999893)
Colorectal Neoplasms  (Score: 0.999893)
Osteosarcoma  (Score: 0.985791)
Stomach Neoplasms  (Score: 0.985791)
Osteosarcoma  (Score: 0.985791)
Stomach Neoplasms  (Score: 0.985791)
Thyroid Neoplasms  (Score: 0.731059)
Carcinoma, Non-Small-Cell Lung  (Score: 0.731059)
Retinoblastoma  (Score: 0.731059)
Adenocarcinoma of Lung  (Score: 0.731059)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:C536914
Disease Name:Thyroid cancer, medullary
Category:MeSH
Type:Neoplasms
Define:A neuroendocrine carcinoma that originates in the C-cells of the THYROID GLAND; about 10-20% of cases are familial. It occurs sporadically or is associated with MULTIPLE ENDOCRINE NEOPLASIA SYNDROMES. Germline and somatic mutations in RET and NTRK1 genes have been identified. OMIM: 155240
Alias:

 

Disease Association Statistics

Total Associated ncRNA Number:8   
More Information
Causal ncRNA Number:0
Network:
Top Causal ncRNAs:
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:33407723
Disease Name:Thyroid cancer, medullary
Sample:medullary thyroid tumor tissues
Dysfunction Pattern:Expression [highly expressed]
Validated Method:qRT-PCR
Description:Here we have tested three up-regulated (RMST, FTX, IPW) and one down-regulated (RMRP) lncRNAs in our samples (formalin fixed paraffin embedded tissues from twenty-one MEN2 and ten sMTC patients) by RT-qPCR analysis.
Causality:No
Causal Description:
Clinical-realted Application: