Entry Detail

General Information

Database ID: LDA0021825
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:GAS5
Full Name:growth arrest specific 5
Category:LncRNA
Species:Homo sapiens
Synonyms:NCRNA00030|SNHG2
Chromosome:1
Strand:-
Coordinate:
Start Site(bp):173863899End Site(bp):173868882
External Links:
Ensembl ID:ENSG00000234741
Ensembl Transcript ID:N/A
Entrez Gene:60674.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:128   
More Information
Causal Disease Number:78
Network:
Top Causal Diseases:
Ovarian Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Breast Neoplasms  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Glioma  (Score: 1)
Osteosarcoma  (Score: 1)
Arthritis, Rheumatoid  (Score: 1)
Osteosarcoma  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:11714D016640
Disease Name:gestational diabetesDiabetes, Gestational
Category:Disease OntologyMeSH
Type:Urogenital Diseases
Define:A diabetes mellitus that manifests during pregnancy.Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
Alias:GDM//Gestational diabetes mellitus//Maternal gestational diabetes mellitusDiabetes, Gestational//Diabetes, Pregnancy-Induced//Diabetes, Pregnancy Induced//Pregnancy-Induced Diabetes//Gestational Diabetes//Diabetes Mellitus, Gestational//Gestational Diabetes Mellitus

 

Disease Association Statistics

Total Associated ncRNA Number:14   
More Information
Causal ncRNA Number:6
Network:
Top Causal ncRNAs:
MALAT1  (Score: 0.731059)
hsa_circ_0001578  (Score: 0.731059)
hsa_circ_0005243  (Score: 0.731059)
MALAT1  (Score: 0.731059)
hsa_circ_0001578  (Score: 0.731059)
hsa_circ_0005243  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:RIP//IP
Weak Evidence:

 

Reference

[1] PubMed ID:35178132
Disease Name:Diabetes, Gestational
Sample:peripheral blood of pregnant women with GDM
Dysfunction Pattern:Expression(lower expressed)
Validated Method:RIP//IP
Description:The lncRNA GAS5 was downregulated in the peripheral blood of pregnant women with GDM compared with normal pregnant women.
Causality:No
Causal Description:
Clinical-realted Application: