Entry Detail

General Information

Database ID: LDA0021830
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:GAS5
Full Name:growth arrest specific 5
Category:LncRNA
Species:Homo sapiens
Synonyms:NCRNA00030|SNHG2
Chromosome:1
Strand:-
Coordinate:
Start Site(bp):173863899End Site(bp):173868882
External Links:
Ensembl ID:ENSG00000234741
Ensembl Transcript ID:N/A
Entrez Gene:60674.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:128   
More Information
Causal Disease Number:78
Network:
Top Causal Diseases:
Ovarian Neoplasms  (Score: 1)
Breast Neoplasms  (Score: 1)
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Breast Neoplasms  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Glioma  (Score: 1)
Osteosarcoma  (Score: 1)
Arthritis, Rheumatoid  (Score: 1)
Osteosarcoma  (Score: 1)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:D008103
Disease Name:Liver Cirrhosis
Category:MeSH
Type:Digestive System Diseases
Define:Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Alias:Liver Cirrhosis//Hepatic Cirrhosis//Cirrhosis, Hepatic//Cirrhosis, Liver//Fibrosis, Liver//Liver Fibrosis

 

Disease Association Statistics

Total Associated ncRNA Number:18   
More Information
Causal ncRNA Number:12
Network:
Top Causal ncRNAs:
lnc-ADD3-AS1  (Score: 0.731059)
CREBBP  (Score: 0.731059)
SCARNA10  (Score: 0.731059)
circFBXW4  (Score: 0.731059)
MBI‑52  (Score: 0.731059)
NEAT1  (Score: 0.731059)
lnc-ADD3-AS1  (Score: 0.731059)
CREBBP  (Score: 0.731059)
SCARNA10  (Score: 0.731059)
circFBXW4  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:32413995
Disease Name:Liver Cirrhosis
Sample:plasma
Dysfunction Pattern:Expression[highly expressed]
Validated Method:qRT-PCR
Description:Plasma GAS5 expression was significantly higher in patients with advanced fibrosis than in those without.
Causality:No
Causal Description:
Clinical-realted Application: