Entry Detail

General Information

Database ID: LDA0021976
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:APTR
Full Name:Alu-mediated CDKN1A/p21 transcriptional regulator
Category:LncRNA
Species:Homo sapiens
Synonyms:RSBN1L-AS1
Chromosome:7
Strand:-
Coordinate:
Start Site(bp):77657660End Site(bp):77697345
External Links:
Ensembl ID:ENSG00000214293
Ensembl Transcript ID:N/A
Entrez Gene:100505854.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:8   
More Information
Causal Disease Number:6
Network:
Top Causal Diseases:
Osteosarcoma  (Score: 0.731059)
uterine fibroid  (Score: 0.731059)
Osteosarcoma  (Score: 0.731059)
uterine fibroid  (Score: 0.731059)
Stomach Neoplasms  (Score: 0.548294)
Stomach Neoplasms  (Score: 0.548294)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:2394D010051
Disease Name:ovarian cancerOvarian Neoplasms
Category:Disease OntologyMeSH
Type:Neoplasms
Define:A female reproductive organ cancer that is located_in the ovary.Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
Alias:malignant Ovarian tumor//malignant tumour of ovary//ovarian neoplasm//ovary neoplasm//primary ovarian cancer//tumor of the OvaryOvarian Neoplasms//Neoplasm, Ovarian//Ovarian Neoplasm//Ovary Neoplasms//Neoplasm, Ovary//Neoplasms, Ovary//Ovary Neoplasm//Neoplasms, Ovarian//Ovary Cancer//Cancer, Ovary//Cancers, Ovary//Ovary Cancers//Ovarian Cancer//Cancer, Ovarian//Cancers, Ovarian//Ovarian Cancers//Cancer of Ovary//Cancer of the Ovary

 

Disease Association Statistics

Total Associated ncRNA Number:478   
More Information
Causal ncRNA Number:418
Network:
Top Causal ncRNAs:
PVT1  (Score: 1)
ATB  (Score: 1)
GAS5  (Score: 1)
PVT1  (Score: 1)
KCNQ1OT1  (Score: 1)
ATB  (Score: 1)
XIST  (Score: 1)
SNHG3  (Score: 1)
NEAT1  (Score: 1)
KCNQ1OT1  (Score: 1)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:31098301
Disease Name:Ovarian Neoplasms
Sample:ovarian cancer tissues
Dysfunction Pattern:Expression[lower expressed]
Validated Method:qRT-PCR
Description:qPCR results indicated marked upregulation of CDKN2A-AS1, C7orf55, LINC00184, HEIH, and ZEB2 expression, whereas that of SNHG3, LINC00630, LOC100133669, APTR, LINC-PINT, and SEMA5A was downregulated in OC tissues as compared with levels in normal ovary tissues (Fig. ?(Fig.5b5b).
Causality:No
Causal Description:
Clinical-realted Application: