Entry Detail


General Information

Database ID: LDA0022410
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:CDKN2B-AS1
Full Name:CDKN2B antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:ANRIL|CDKN2B-AS|CDKN2BAS|NCRNA00089|PCAT12|p15AS
Chromosome:9
Strand:+
Coordinate:
Start Site(bp):21994791End Site(bp):22121097
External Links:
Ensembl ID:ENSG00000240498
Ensembl Transcript ID:N/A
Entrez Gene:100048912.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:96   
More Information
Causal Disease Number:54
Network:
Top Causal Diseases:
Breast Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Breast Neoplasms  (Score: 1)
Glioma  (Score: 0.999893)
Leukemia, Myeloid, Acute  (Score: 0.999893)
Ovarian Neoplasms  (Score: 0.999893)
Osteosarcoma  (Score: 0.999893)
Leukemia, Myeloid, Acute  (Score: 0.999893)
Glioma  (Score: 0.999893)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:8778D003424
Disease Name:Crohn's diseaseCrohn Disease
Category:Disease OntologyMeSH
Type:Digestive System Diseases
Define:An intestinal disease that involves inflammation located_in intestine.A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
Alias:Crohn disease//Crohn's disease of colon//Crohn's disease of large bowel//Granulomatous Colitis//Pediatric Crohn's diseaseCrohn Disease//Crohn's Enteritis//Regional Enteritis//Crohn's Disease//Crohns Disease//Inflammatory Bowel Disease 1//Enteritis, Granulomatous//Granulomatous Enteritis//Enteritis, Regional//Ileocolitis//Colitis, Granulomatous//Granulomatous Colitis//Ileitis, Terminal//Terminal Ileitis//Ileitis, Regional//Regional Ileitides//Regional Ileitis

 

Disease Association Statistics

Total Associated ncRNA Number:24   
More Information
Causal ncRNA Number:12
Network:
Top Causal ncRNAs:
hsa_circ_102610  (Score: 0.985791)
hsa_circ_103124  (Score: 0.985791)
hsa_circ_102610  (Score: 0.985791)
hsa_circ_103124  (Score: 0.985791)
MALAT1  (Score: 0.731059)
PELATON  (Score: 0.731059)
hsa_circ_103765  (Score: 0.731059)
circGMCL1  (Score: 0.731059)
MALAT1  (Score: 0.731059)
PELATON  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:30665494
Disease Name:Crohn Disease
Sample:Inflamed intestinal mucosa
Dysfunction Pattern:Expression[lower expressed]
Validated Method:qRT-PCR
Description:LncRNA ANRIL expression was decreased in patients with A-CD compared with patients with R-CD (P < 0.001) and controls (P < 0.001) and was also reduced in patients with R-CD compared with controls (P < 0.001).
Causality:No
Causal Description:
Clinical-realted Application: