Entry Detail

General Information

Database ID: LDA0022412
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Unknown

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:CDKN2B-AS1
Full Name:CDKN2B antisense RNA 1
Category:LncRNA
Species:Homo sapiens
Synonyms:ANRIL|CDKN2B-AS|CDKN2BAS|NCRNA00089|PCAT12|p15AS
Chromosome:9
Strand:+
Coordinate:
Start Site(bp):21994791End Site(bp):22121097
External Links:
Ensembl ID:ENSG00000240498
Ensembl Transcript ID:N/A
Entrez Gene:100048912.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:96   
More Information
Causal Disease Number:54
Network:
Top Causal Diseases:
Breast Neoplasms  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Carcinoma, Hepatocellular  (Score: 1)
Breast Neoplasms  (Score: 1)
Glioma  (Score: 0.999893)
Leukemia, Myeloid, Acute  (Score: 0.999893)
Ovarian Neoplasms  (Score: 0.999893)
Osteosarcoma  (Score: 0.999893)
Leukemia, Myeloid, Acute  (Score: 0.999893)
Glioma  (Score: 0.999893)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:11946D000026
Disease Name:obsolete habitual abortionAbortion, Habitual
Category:Disease OntologyMeSH
Type:Urogenital Diseases
Define:Three or more consecutive spontaneous abortions.
Alias:Aborter - recurrent//Habitual aborter//Habitual aborter - unspecified (disorder)//Habitual aborter NOS (disorder)//chronic spontaneous abortion//recurrent abortion (disorder)//recurrent miscarriageAbortion, Habitual//Habitual Abortion//Habitual Abortions//Abortion, Recurrent//Recurrent Abortion//Recurrent Abortions//Miscarriage, Recurrent//Recurrent Miscarriage//Recurrent Miscarriages//Recurrent Early Pregnancy Loss

 

Disease Association Statistics

Total Associated ncRNA Number:16   
More Information
Causal ncRNA Number:2
Network:
Top Causal ncRNAs:
lnc-CES1-1  (Score: 0.731059)
lnc-CES1-1  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:Genotyping
Weak Evidence:

 

Reference

[1] PubMed ID:34234511
Disease Name:Abortion, Habitual
Sample:Southern Chinese Population
Dysfunction Pattern:Mutation(rs2151280 )
Validated Method:Genotyping
Description:Our results showed that the ANRIL rs2151280 GG genotype was associated with increased susceptibility to recurrent miscarriage (GG vs AA: adjusted OR=1.527, 95% CI=1.051-2.218, p=0.0262; GG vs AG/AA adjusted OR=1.460, 95% CI=1.021-2.089, p=0.0381).
Causality:No
Causal Description:
Clinical-realted Application: