Entry Detail


General Information

Database ID: LDA0022767
Species: Homo sapiens
Confidence Score: 0.731059
Contents: >> ncRNA Information
>> ncRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference
Causality: Unknown
Clinical Significance: Yes

 


ncRNA Information

Reference Genome Note: GRCh38 for human lncRNAs; GRCm39 for mouse lncRNAs; mRatBN7.2 for rat lncRNAs; hg19 for human circRNAs; mm9 for mouse circRNAs.

ncRNA Symbol:CCAT1
Full Name:colon cancer associated transcript 1
Category:LncRNA
Species:Homo sapiens
Synonyms:CARLO5|CARLo-5|onco-lncRNA-40
Chromosome:8
Strand:-
Coordinate:
Start Site(bp):127207382End Site(bp):127219268
External Links:
Ensembl ID:N/A
Ensembl Transcript ID:N/A
Entrez Gene:100507056.0
NONCODE ID:N/A
RefSeq Accession:N/A

 

ncRNA Association Statistics

Total Associated Disease Number:46   
More Information
Causal Disease Number:30
Network:
Top Causal Diseases:
Colorectal Neoplasms  (Score: 1)
Colorectal Neoplasms  (Score: 1)
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Carcinoma, Non-Small-Cell Lung  (Score: 1)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.999893)
Stomach Neoplasms  (Score: 0.999893)
Squamous Cell Carcinoma of Head and Neck  (Score: 0.999893)
Adenocarcinoma of Lung  (Score: 0.999893)
Adenocarcinoma of Lung  (Score: 0.999893)
Stomach Neoplasms  (Score: 0.999893)
More Information

 

 

Disease Information

 Disease OntologyMeSH
Disease ID:DOID:10591D011225
Disease Name:pre-eclampsiaPre-Eclampsia
Category:Disease OntologyMeSH
Type:Urogenital Diseases
Define:A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
Alias:gestational hypertension//hypertension induced by pregnancy//pre-eclamptic toxaemia//preeclampsia//preeclampsia/eclampsia//pregnancy associated hypertension//pregnancy toxemia//proteinuric hypertension of pregnancy//toxaemia of pregnancyPre-Eclampsia//Pre Eclampsia//Preeclampsia//Pregnancy Toxemias//Pregnancy Toxemia//Toxemia, Pregnancy//Edema-Proteinuria-Hypertension Gestosis//Edema Proteinuria Hypertension Gestosis//Gestosis, Edema-Proteinuria-Hypertension//Hypertension-Edema-Proteinuria Gestosis//Gestosis, Hypertension-Edema-Proteinuria//Hypertension Edema Proteinuria Gestosis//Toxemia Of Pregnancy//Of Pregnancies, Toxemia//Of Pregnancy, Toxemia//Pregnancies, Toxemia Of//Pregnancy, Toxemia Of//Toxemia Of Pregnancies//EPH Complex//EPH Toxemias//EPH Toxemia//Toxemia, EPH//Toxemias, EPH//EPH Gestosis//Gestosis, EPH//Toxemias, Pregnancy//Preeclampsia Eclampsia 1//1, Preeclampsia Eclampsia//1s, Preeclampsia Eclampsia//Eclampsia 1, Preeclampsia//Eclampsia 1s, Preeclampsia//Preeclampsia Eclampsia 1s//Proteinuria-Edema-Hypertension Gestosis//Gestosis, Proteinuria-Edema-Hypertension//Proteinuria Edema Hypertension Gestosis

 

Disease Association Statistics

Total Associated ncRNA Number:42   
More Information
Causal ncRNA Number:36
Network:
Top Causal ncRNAs:
HOTAIR  (Score: 0.985791)
HOTAIR  (Score: 0.985791)
MALAT1  (Score: 0.985791)
MALAT1  (Score: 0.985791)
DLX6-AS1  (Score: 0.731059)
UCA1  (Score: 0.731059)
SNHG14  (Score: 0.731059)
APOA1-AS  (Score: 0.731059)
uc.187  (Score: 0.731059)
DANCR  (Score: 0.731059)
More Information

 

Evidence Support

Strong Evidence:qRT-PCR
Weak Evidence:

 

Reference

[1] PubMed ID:35733554
Disease Name:Pre-Eclampsia
Sample:Egyptian patients
Dysfunction Pattern:Expression(highly expressed)
Validated Method:qRT-PCR
Description:Expression levels of CCAT1 and CDK4 differed significantly between the study groups.preeclamptic patients having the highest level of CCAT1in comparison with control group, However, preeclamptic patients having lower level of CDK4 than controls.
Causality:No
Causal Description:
Clinical-realted Application:Expression levels of CCAT1 and CDK4 differed significantly between the study groups.preeclamptic patients having the highest level of CCAT1in comparison with control group, However, preeclamptic patients having lower level of CDK4 than controls.